I use to run NOS on my banshee and i ran it with 7degrees of advance and on alcohol. I would have to say that 2 degrees is nothing just make sure you have good fuel pressure and the right fuel jet to match the amount of NOS that you are spraying to it. And check your plugs after you spray. If your jetting is good it will be fine. if not plan on replacing some plugs, cylinders head, and pistons of course.
Hope that helps
Steve.